The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis

We identified a series of novel 7-phenyl benzoxaborole compounds with activity against Mycobacterium tuberculosis. Compounds had a range of activity with inhibitory concentrations (IC(90)) as low as 5.1 μM and no cytotoxicity against eukaryotic cells (IC(50) > 50 μM). Compounds were active agains...

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Detalles Bibliográficos
Autores principales: Korkegian, Aaron, O'Malley, Theresa, Xia, Yi, Zhou, Yasheen, Carter, David S., Sunde, Bjorn, Flint, Lindsay, Thompson, Dean, Ioerger, Thomas R., Sacchettini, Jim, Alley, M.R.K., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854369/
https://www.ncbi.nlm.nih.gov/pubmed/29523334
http://dx.doi.org/10.1016/j.tube.2017.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854369/
https://www.ncbi.nlm.nih.gov/pubmed/29523334
http://dx.doi.org/10.1016/j.tube.2017.11.003

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