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The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis
We identified a series of novel 7-phenyl benzoxaborole compounds with activity against Mycobacterium tuberculosis. Compounds had a range of activity with inhibitory concentrations (IC(90)) as low as 5.1 μM and no cytotoxicity against eukaryotic cells (IC(50) > 50 μM). Compounds were active agains...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Churchill Livingstone
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854369/ https://www.ncbi.nlm.nih.gov/pubmed/29523334 http://dx.doi.org/10.1016/j.tube.2017.11.003 |