Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint

1,25-dihydroxyvitaminD(3) (1,25(OH)(2)D(3)), has potent anti-inflammatory effects, including suppression of IL-17 + and IFNγ+ T cells implicated in rheumatoid arthritis (RA), but efficacy at the site of active disease is unclear. To investigate this, T cells from synovial fluid (SF) and paired blood...

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Detalles Bibliográficos
Autores principales: Jeffery, Louisa E., Henley, Peter, Marium, Nefisa, Filer, Andrew, Sansom, David M., Hewison, Martin, Raza, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854374/
https://www.ncbi.nlm.nih.gov/pubmed/29066221
http://dx.doi.org/10.1016/j.jaut.2017.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854374/
https://www.ncbi.nlm.nih.gov/pubmed/29066221
http://dx.doi.org/10.1016/j.jaut.2017.10.001

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