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Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate

Scabin is a mono-ADP-ribosyltransferase enzyme and is a putative virulence factor produced by the plant pathogen, Streptomyces scabies. Previously, crystal structures of Scabin were solved in the presence and absence of substrate analogues and inhibitors. Herein, experimental (hydrogen-deuterium exc...

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Detalles Bibliográficos
Autores principales: Lugo, Miguel R., Lyons, Bronwyn, Lento, Cristina, Wilson, Derek J., Merrill, A. Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854381/
https://www.ncbi.nlm.nih.gov/pubmed/29543870
http://dx.doi.org/10.1371/journal.pone.0194425