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L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice

Sphingolipids are a diverse group of lipids with important roles in beta-cell biology regulating insulin folding and controlling apoptosis. Sphingolipid biosynthesis begins with the condensation of L-serine and palmitoyl-CoA. Here we tested the effect of L-serine supplementation on autoimmune diabet...

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Detalles Bibliográficos
Autores principales: Holm, Laurits J., Haupt-Jorgensen, Martin, Larsen, Jesper, Giacobini, Jano D., Bilgin, Mesut, Buschard, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854405/
https://www.ncbi.nlm.nih.gov/pubmed/29543915
http://dx.doi.org/10.1371/journal.pone.0194414