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L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice
Sphingolipids are a diverse group of lipids with important roles in beta-cell biology regulating insulin folding and controlling apoptosis. Sphingolipid biosynthesis begins with the condensation of L-serine and palmitoyl-CoA. Here we tested the effect of L-serine supplementation on autoimmune diabet...
Autores principales: | Holm, Laurits J., Haupt-Jorgensen, Martin, Larsen, Jesper, Giacobini, Jano D., Bilgin, Mesut, Buschard, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854405/ https://www.ncbi.nlm.nih.gov/pubmed/29543915 http://dx.doi.org/10.1371/journal.pone.0194414 |
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