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Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections

There is great interest in passive transfer of broadly neutralizing antibodies (bnAbs) and engineered bispecific antibodies (Abs) for prevention of HIV-1 infections due to their in vitro neutralization breadth and potency against global isolates and long in vivo half-lives. We compared the potential...

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Detalles Bibliográficos
Autores principales: Wagh, Kshitij, Seaman, Michael S., Zingg, Marshall, Fitzsimons, Tomas, Barouch, Dan H., Burton, Dennis R., Connors, Mark, Ho, David D., Mascola, John R., Nussenzweig, Michel C., Ravetch, Jeffrey, Gautam, Rajeev, Martin, Malcolm A., Montefiori, David C., Korber, Bette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854441/
https://www.ncbi.nlm.nih.gov/pubmed/29505593
http://dx.doi.org/10.1371/journal.ppat.1006860