A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism

Amino-acid coevolution can be referred to mutational compensatory patterns preserving the function of a protein. Viral envelope glycoproteins, which mediate entry of enveloped viruses into their host cells, are shaped by coevolution signals that confer to viruses the plasticity to evade neutralizing...

Descripción completa

Detalles Bibliográficos
Autores principales: Douam, Florian, Fusil, Floriane, Enguehard, Margot, Dib, Linda, Nadalin, Francesca, Schwaller, Loïc, Hrebikova, Gabriela, Mancip, Jimmy, Mailly, Laurent, Montserret, Roland, Ding, Qiang, Maisse, Carine, Carlot, Emilie, Xu, Ke, Verhoeyen, Els, Baumert, Thomas F., Ploss, Alexander, Carbone, Alessandra, Cosset, François-Loïc, Lavillette, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854445/
https://www.ncbi.nlm.nih.gov/pubmed/29505618
http://dx.doi.org/10.1371/journal.ppat.1006908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854445/
https://www.ncbi.nlm.nih.gov/pubmed/29505618
http://dx.doi.org/10.1371/journal.ppat.1006908

Ejemplares similares