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LPA signaling is regulated through the primary cilium: a novel target in glioblastoma

The primary cilium is a ubiquitous organelle presented on most human cells. It is a crucial signaling hub for multiple pathways including growth factor and G-protein coupled receptors. Loss of primary cilia, observed in various cancers, has been shown to affect cell proliferation. Primary cilia form...

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Detalles Bibliográficos
Autores principales: Loskutov, Yuriy V., Griffin, Caryn L., Marinak, Kristina M., Bobko, Andrey, Margaryan, Naira V., Geldenhuys, Werner J., Sarkaria, Jann N., Pugacheva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854509/
https://www.ncbi.nlm.nih.gov/pubmed/29321663
http://dx.doi.org/10.1038/s41388-017-0049-3