Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction

Transcription factors are fundamental regulators of gene transcription, and many diseases, such as heart diseases, are associated with deregulation of transcriptional networks. In the adult heart, zinc-finger transcription factor GATA4 is a critical regulator of cardiac repair and remodelling. Previ...

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Detalles Bibliográficos
Autores principales: Kinnunen, Sini M., Tölli, Marja, Välimäki, Mika J., Gao, Erhe, Szabo, Zoltan, Rysä, Jaana, Ferreira, Mónica P. A., Ohukainen, Pauli, Serpi, Raisa, Correia, Alexandra, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Santos, Hélder A., Ruskoaho, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854571/
https://www.ncbi.nlm.nih.gov/pubmed/29545582
http://dx.doi.org/10.1038/s41598-018-22830-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854571/
https://www.ncbi.nlm.nih.gov/pubmed/29545582
http://dx.doi.org/10.1038/s41598-018-22830-8

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