Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice

Seasonal influenza vaccines have proven to be effective against well-matched viruses in healthy adults. However, rapid accumulation of mutations in the main antigenic surface proteins of influenza can compromise the efficiency of flu vaccines. Occasionally, influenza pandemics arise and present a di...

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Detalles Bibliográficos
Autores principales: Luo, Yuan, Mohan, Teena, Zhu, Wandi, Wang, Chao, Deng, Lei, Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854580/
https://www.ncbi.nlm.nih.gov/pubmed/29545521
http://dx.doi.org/10.1038/s41598-018-22874-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854580/
https://www.ncbi.nlm.nih.gov/pubmed/29545521
http://dx.doi.org/10.1038/s41598-018-22874-w

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