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Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice
Seasonal influenza vaccines have proven to be effective against well-matched viruses in healthy adults. However, rapid accumulation of mutations in the main antigenic surface proteins of influenza can compromise the efficiency of flu vaccines. Occasionally, influenza pandemics arise and present a di...
Autores principales: | Luo, Yuan, Mohan, Teena, Zhu, Wandi, Wang, Chao, Deng, Lei, Wang, Bao-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854580/ https://www.ncbi.nlm.nih.gov/pubmed/29545521 http://dx.doi.org/10.1038/s41598-018-22874-w |
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