On-target action of anti-tropomyosin drugs regulates glucose metabolism

The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice....

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Detalles Bibliográficos
Autores principales: Kee, Anthony J., Chagan, Jayshan, Chan, Jeng Yie, Bryce, Nicole S., Lucas, Christine A., Zeng, Jun, Hook, Jeff, Treutlein, Herbert, Laybutt, D. Ross, Stehn, Justine R., Gunning, Peter W., Hardeman, Edna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854615/
https://www.ncbi.nlm.nih.gov/pubmed/29545590
http://dx.doi.org/10.1038/s41598-018-22946-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854615/
https://www.ncbi.nlm.nih.gov/pubmed/29545590
http://dx.doi.org/10.1038/s41598-018-22946-x

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