Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here we show that during atherogenesis Treg cells lose Foxp3 expression and their immunosuppressive function, leading to the conversion of a fraction of these cells into T follicular helper (Tfh) cells. We s...

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Detalles Bibliográficos
Autores principales: Gaddis, Dalia E., Padgett, Lindsey E., Wu, Runpei, McSkimming, Chantel, Romines, Veronica, Taylor, Angela M., McNamara, Coleen A., Kronenberg, Mitchell, Crotty, Shane, Thomas, Michael J., Sorci-Thomas, Mary G., Hedrick, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854619/
https://www.ncbi.nlm.nih.gov/pubmed/29545616
http://dx.doi.org/10.1038/s41467-018-03493-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854619/
https://www.ncbi.nlm.nih.gov/pubmed/29545616
http://dx.doi.org/10.1038/s41467-018-03493-5

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