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Evaluation of 25% Poloxamer As a Slow Release Carrier for Morphine in a Rat Model

The objectives of this study were to evaluate poloxamer as a slow release carrier for morphine (M) and potential tissue irritation after subcutaneous poloxamer–morphine (PM) injection in a rat model. Based on the result of a previous in vitro work, 25% poloxamer, with and without morphine, and salin...

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Detalles Bibliográficos
Autores principales: Sulimai, Nurul H., Ko, Jeff C., Jones-Hall, Yava L., Weng, Hsin-Yi, Deng, Meng, Breur, Gert J., Knipp, Gregory T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854640/
https://www.ncbi.nlm.nih.gov/pubmed/29594153
http://dx.doi.org/10.3389/fvets.2018.00019