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East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease

Cyclic adenosine monophosphate phosphodiesterases (PDEs) regulate pro-inflammatory cytokine production. One isoform, PDE4, is overactive in chronic relapsing inflammatory skin diseases: psoriasis and eczema/atopic dermatitis, and in several cancers. East Indian sandalwood oil (EISO) has significant...

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Detalles Bibliográficos
Autores principales: Sharma, Manju, Levenson, Corey, Browning, John C., Becker, Emily M., Clements, Ian, Castella, Paul, Cox, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854648/
https://www.ncbi.nlm.nih.gov/pubmed/29593534
http://dx.doi.org/10.3389/fphar.2018.00200