Mitochondrial Sirtuin 4 Resolves Immune Tolerance in Monocytes by Rebalancing Glycolysis and Glucose Oxidation Homeostasis

The goal of this investigation was to define the molecular mechanism underlying physiologic conversion of immune tolerance to resolution of the acute inflammatory response, which is unknown. An example of this knowledge gap and its clinical importance is the broad-based energy deficit and immunometa...

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Detalles Bibliográficos
Autores principales: Tao, Jie, Zhang, Jingpu, Ling, Yun, McCall, Charles E., Liu, Tie Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854658/
https://www.ncbi.nlm.nih.gov/pubmed/29593712
http://dx.doi.org/10.3389/fimmu.2018.00419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854658/
https://www.ncbi.nlm.nih.gov/pubmed/29593712
http://dx.doi.org/10.3389/fimmu.2018.00419

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