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Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy

The general transcription factor IID (TFIID) is the first component of the preinitiation complex (PIC) to bind the core promoter of RNA polymerase II transcribed genes. Despite its critical role in protein-encoded gene expression, how TFIID engages promoter DNA remains elusive. We have previously re...

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Detalles Bibliográficos
Autores principales: Curran, Elizabeth C., Wang, Hui, Hinds, Thomas R., Zheng, Ning, Wang, Edith H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854669/
https://www.ncbi.nlm.nih.gov/pubmed/29545534
http://dx.doi.org/10.1038/s41598-018-22879-5