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Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy
The general transcription factor IID (TFIID) is the first component of the preinitiation complex (PIC) to bind the core promoter of RNA polymerase II transcribed genes. Despite its critical role in protein-encoded gene expression, how TFIID engages promoter DNA remains elusive. We have previously re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854669/ https://www.ncbi.nlm.nih.gov/pubmed/29545534 http://dx.doi.org/10.1038/s41598-018-22879-5 |