Cargando…

Solution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity

Large-conductance Ca(2+)- and voltage-dependent K(+) (BK) channels display diverse biological functions while their pore-forming α subunit is coded by a single Slo1 gene. The variety of BK channels is correlated with the effects of BKα coexpression with auxiliary β (β1-β4) subunits, as well as newly...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanting, Lan, Wenxian, Yan, Zhenzhen, Gao, Jing, Liu, Xinlian, Wang, Sheng, Guo, Xiying, Wang, Chunxi, Zhou, Hu, Ding, Jiuping, Cao, Chunyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854672/
https://www.ncbi.nlm.nih.gov/pubmed/29545539
http://dx.doi.org/10.1038/s41598-018-23016-y