Mitochondrial Molecular Abnormalities Revealed by Proteomic Analysis of Hippocampal Organelles of Mice Triple Transgenic for Alzheimer Disease

Mitochondrial dysfunction is implicated in the pathogenesis of Alzheimer’s disease (AD). However, the precise mitochondrial molecular deficits in AD remain poorly understood. Mitochondrial and nuclear proteomic analysis in mature male triple transgenic AD mice (PS1M146V/APPSwe/TauP301L) by two-dimen...

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Detalles Bibliográficos
Autores principales: Yu, Haitao, Lin, Xuemei, Wang, Dian, Zhang, Zaijun, Guo, Yi, Ren, Xiaohu, Xu, Benhong, Yuan, Jianhui, Liu, Jianjun, Spencer, Peter S., Wang, Jian-Zhi, Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854685/
https://www.ncbi.nlm.nih.gov/pubmed/29593495
http://dx.doi.org/10.3389/fnmol.2018.00074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854685/
https://www.ncbi.nlm.nih.gov/pubmed/29593495
http://dx.doi.org/10.3389/fnmol.2018.00074

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