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Voltage gating of mechanosensitive PIEZO channels

Mechanosensitive PIEZO ion channels are evolutionarily conserved proteins whose presence is critical for normal physiology in multicellular organisms. Here we show that, in addition to mechanical stimuli, PIEZO channels are also powerfully modulated by voltage and can even switch to a purely voltage...

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Detalles Bibliográficos
Autores principales: Moroni, Mirko, Servin-Vences, M. Rocio, Fleischer, Raluca, Sánchez-Carranza, Oscar, Lewin, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854696/
https://www.ncbi.nlm.nih.gov/pubmed/29545531
http://dx.doi.org/10.1038/s41467-018-03502-7