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Voltage gating of mechanosensitive PIEZO channels
Mechanosensitive PIEZO ion channels are evolutionarily conserved proteins whose presence is critical for normal physiology in multicellular organisms. Here we show that, in addition to mechanical stimuli, PIEZO channels are also powerfully modulated by voltage and can even switch to a purely voltage...
Autores principales: | Moroni, Mirko, Servin-Vences, M. Rocio, Fleischer, Raluca, Sánchez-Carranza, Oscar, Lewin, Gary R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854696/ https://www.ncbi.nlm.nih.gov/pubmed/29545531 http://dx.doi.org/10.1038/s41467-018-03502-7 |
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