Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance

Influenza viruses are respiratory pathogens that are responsible for seasonal influenza and sporadic influenza pandemic. The therapeutic efficacy of current influenza vaccines and small molecule antiviral drugs is limited due to the emergence of multidrug-resistant influenza viruses. In response to...

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Detalles Bibliográficos
Autores principales: Zhang, Jiantao, Hu, Yanmei, Foley, Christopher, Wang, Yuanxiang, Musharrafieh, Rami, Xu, Shuting, Zhang, Yongtao, Ma, Chunlong, Hulme, Christopher, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854701/
https://www.ncbi.nlm.nih.gov/pubmed/29545578
http://dx.doi.org/10.1038/s41598-018-22875-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854701/
https://www.ncbi.nlm.nih.gov/pubmed/29545578
http://dx.doi.org/10.1038/s41598-018-22875-9

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