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Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance
Influenza viruses are respiratory pathogens that are responsible for seasonal influenza and sporadic influenza pandemic. The therapeutic efficacy of current influenza vaccines and small molecule antiviral drugs is limited due to the emergence of multidrug-resistant influenza viruses. In response to...
Autores principales: | Zhang, Jiantao, Hu, Yanmei, Foley, Christopher, Wang, Yuanxiang, Musharrafieh, Rami, Xu, Shuting, Zhang, Yongtao, Ma, Chunlong, Hulme, Christopher, Wang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854701/ https://www.ncbi.nlm.nih.gov/pubmed/29545578 http://dx.doi.org/10.1038/s41598-018-22875-9 |
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