Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives

Synthesis, characterization, and investigation of antiproliferative activities against human cancer cell lines (MV4-11, MCF-7, and A549) and Toxoplasma gondii parasite of twelve novel 2,4-diaminotriazine-thiazoles are presented. The toxicity of the compounds was studied at three different cell types...

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Detalles Bibliográficos
Autores principales: Łączkowski, Krzysztof Z., Anusiak, Joanna, Świtalska, Marta, Dzitko, Katarzyna, Cytarska, Joanna, Baranowska-Łączkowska, Angelika, Plech, Tomasz, Paneth, Agata, Wietrzyk, Joanna, Białczyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854716/
https://www.ncbi.nlm.nih.gov/pubmed/29576720
http://dx.doi.org/10.1007/s00044-018-2136-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854716/
https://www.ncbi.nlm.nih.gov/pubmed/29576720
http://dx.doi.org/10.1007/s00044-018-2136-6

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