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Endothelial-dependent dilation following chronic hypoxia involves TRPV4-mediated activation of endothelial BK channels
Following chronic hypoxia (CH), the systemic vasculature exhibits blunted vasoconstriction due to endothelial-dependent hyperpolarization (EDH). Previous data demonstrate that subsequent to CH, EDH-mediated vasodilation switches from a reliance on SK(ca) and IK(ca) channels to activation of the endo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854740/ https://www.ncbi.nlm.nih.gov/pubmed/29380056 http://dx.doi.org/10.1007/s00424-018-2112-5 |