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Endothelial-dependent dilation following chronic hypoxia involves TRPV4-mediated activation of endothelial BK channels

Following chronic hypoxia (CH), the systemic vasculature exhibits blunted vasoconstriction due to endothelial-dependent hyperpolarization (EDH). Previous data demonstrate that subsequent to CH, EDH-mediated vasodilation switches from a reliance on SK(ca) and IK(ca) channels to activation of the endo...

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Detalles Bibliográficos
Autores principales:	Naik, Jay S., Walker, Benjimen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Ion Channels, Receptors and Transporters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854740/ https://www.ncbi.nlm.nih.gov/pubmed/29380056 http://dx.doi.org/10.1007/s00424-018-2112-5

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