Comparative molecular field analysis and molecular dynamics studies of the dopamine D(2) receptor antagonists without a protonatable nitrogen atom

The dopaminergic hypothesis of schizophrenia is the main concept explaining the direct reasons of schizophrenia and the effectiveness of current antipsychotics. All antipsychotics present on the market are potent dopamine D(2) receptor antagonists or partial agonists. In this work we investigate a s...

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Detalles Bibliográficos
Autores principales: Kaczor, Agnieszka A., Żuk, Justyna, Matosiuk, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854747/
https://www.ncbi.nlm.nih.gov/pubmed/29576721
http://dx.doi.org/10.1007/s00044-018-2137-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854747/
https://www.ncbi.nlm.nih.gov/pubmed/29576721
http://dx.doi.org/10.1007/s00044-018-2137-5

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