Short-Term Fasting Alters Pharmacokinetics of Cytochrome P450 Probe Drugs: Does Protein Binding Play a Role?

BACKGROUND AND OBJECTIVES: Short-term fasting differentially alters cytochrome P450 (CYP) mediated drug metabolism. This has been established by using CYP-enzyme selective probe drugs. However, the observed effects of fasting on the pharmacokinetics of these probe drugs may also include the effects...

Descripción completa

Detalles Bibliográficos
Autores principales: Lammers, Laureen A., Achterbergh, Roos, Romijn, Johannes A., Mathôt, Ron A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854751/
https://www.ncbi.nlm.nih.gov/pubmed/28929443
http://dx.doi.org/10.1007/s13318-017-0437-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854751/
https://www.ncbi.nlm.nih.gov/pubmed/28929443
http://dx.doi.org/10.1007/s13318-017-0437-7

Ejemplares similares