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Production and Purification of High-Titer Newcastle Disease Virus for Use in Preclinical Mouse Models of Cancer

Newcastle disease virus (NDV) is a single-stranded, negative-sense RNA virus in the Paramyxoviridae family. Although primarily an avian pathogen, NDV is a potent oncolytic virus that has been shown to be safe and effective in a variety of preclinical cancer models and human clinical trials. To produ...

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Detalles Bibliográficos
Autores principales: Santry, Lisa A., McAusland, Thomas M., Susta, Leonardo, Wood, Geoffrey A., Major, Pierre P., Petrik, Jim J., Bridle, Byram W., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854916/
https://www.ncbi.nlm.nih.gov/pubmed/29556508
http://dx.doi.org/10.1016/j.omtm.2017.10.004