Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design

The primary goal of rational drug discovery is the identification of selective ligands which act on single or multiple drug targets to achieve the desired clinical outcome through the exploration of total chemical space. To identify such desired compounds, computational approaches are necessary in p...

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Detalles Bibliográficos
Autores principales: Basith, Shaherin, Cui, Minghua, Macalino, Stephani J. Y., Park, Jongmi, Clavio, Nina A. B., Kang, Soosung, Choi, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854945/
https://www.ncbi.nlm.nih.gov/pubmed/29593527
http://dx.doi.org/10.3389/fphar.2018.00128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854945/
https://www.ncbi.nlm.nih.gov/pubmed/29593527
http://dx.doi.org/10.3389/fphar.2018.00128

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