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3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype

Hyperlipidemic state-associated perturbations in the network of factors controlling mitochondrial functions, i. e., morphogenesis machinery and metabolic sensor proteins, produce metabolic inflexibility, insulin resistance and reduced oxidative capacity in skeletal muscle. Moreover, intramyocellular...

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Detalles Bibliográficos
Autores principales: Silvestri, Elena, Cioffi, Federica, De Matteis, Rita, Senese, Rosalba, de Lange, Pieter, Coppola, Maria, Salzano, Anna M., Scaloni, Andrea, Ceccarelli, Michele, Goglia, Fernando, Lanni, Antonia, Moreno, Maria, Lombardi, Assunta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854997/
https://www.ncbi.nlm.nih.gov/pubmed/29593557
http://dx.doi.org/10.3389/fphys.2018.00194