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A thiocyanopalladation/carbocyclization transformation identified through enzymatic screening: stereocontrolled tandem C–SCN and C–C bond formation

Herein we describe a formal thiocyanopalladation/carbocyclization transformation and its parametrization and optimization using a new elevated temperature plate-based version of our visual colorimetric enzymatic screening method for reaction discovery. The carbocyclization step leads to C–SCN bond f...

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Detalles Bibliográficos
Autores principales: Malik, G., Swyka, R. A., Tiwari, V. K., Fei, X., Applegate, G. A., Berkowitz, D. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855125/
https://www.ncbi.nlm.nih.gov/pubmed/29568453
http://dx.doi.org/10.1039/c7sc04083k