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Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro

Hepatocellular carcinoma (HCC) frequently develops from hepatitis C virus (HCV) and hepatitis B virus (HBV) infection. We previously reported that peretinoin, an acyclic retinoid, inhibits HCV replication. This study aimed to examine the influence of peretinoin on the HBV lifecycle. HBV-DNA and cova...

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Detalles Bibliográficos
Autores principales: Murai, Kazuhisa, Shirasaki, Takayoshi, Honda, Masao, Shimizu, Ryogo, Shimakami, Tetsuro, Nakasho, Saki, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Yamashita, Taro, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855541/
https://www.ncbi.nlm.nih.gov/pubmed/29360739
http://dx.doi.org/10.3390/ijms19020108