Solid Lipid Nanoparticles Carrying Temozolomide for Melanoma Treatment. Preliminary In Vitro and In Vivo Studies

Aim: To develop an innovative delivery system for temozolomide (TMZ) in solid lipid nanoparticles (SLN), which has been preliminarily investigated for the treatment of melanoma. Materials and Methods: SLN-TMZ was obtained through fatty acid coacervation. Its pharmacological effects were assessed and...

Descripción completa

Detalles Bibliográficos
Autores principales: Clemente, Nausicaa, Ferrara, Benedetta, Gigliotti, Casimiro Luca, Boggio, Elena, Capucchio, Maria Teresa, Biasibetti, Elena, Schiffer, Davide, Mellai, Marta, Annovazzi, Laura, Cangemi, Luigi, Muntoni, Elisabetta, Miglio, Gianluca, Dianzani, Umberto, Battaglia, Luigi, Dianzani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855544/
https://www.ncbi.nlm.nih.gov/pubmed/29364157
http://dx.doi.org/10.3390/ijms19020255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855544/
https://www.ncbi.nlm.nih.gov/pubmed/29364157
http://dx.doi.org/10.3390/ijms19020255

Ejemplares similares