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Solid Lipid Nanoparticles Carrying Temozolomide for Melanoma Treatment. Preliminary In Vitro and In Vivo Studies

Aim: To develop an innovative delivery system for temozolomide (TMZ) in solid lipid nanoparticles (SLN), which has been preliminarily investigated for the treatment of melanoma. Materials and Methods: SLN-TMZ was obtained through fatty acid coacervation. Its pharmacological effects were assessed and...

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Detalles Bibliográficos
Autores principales:	Clemente, Nausicaa, Ferrara, Benedetta, Gigliotti, Casimiro Luca, Boggio, Elena, Capucchio, Maria Teresa, Biasibetti, Elena, Schiffer, Davide, Mellai, Marta, Annovazzi, Laura, Cangemi, Luigi, Muntoni, Elisabetta, Miglio, Gianluca, Dianzani, Umberto, Battaglia, Luigi, Dianzani, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855544/ https://www.ncbi.nlm.nih.gov/pubmed/29364157 http://dx.doi.org/10.3390/ijms19020255

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