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Role of Disulfide Bonds in Activity and Stability of Tigerinin-1R

Tigerinin-1R (Arg–Val–Cys–Ser–Ala–Ile–Pro–Leu–Pro–Ile–Cys–His–NH(2)), a cationic 12-mer peptide containing a disulfide bond extracted from frog skin secretions, lacks antibacterial activity, but has the ability to stimulate insulin release both in vitro and in vivo. To study the structure–function r...

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Detalles Bibliográficos
Autores principales: Chen, Xiaolong, Hu, Cuihua, Huang, Yibing, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855545/
https://www.ncbi.nlm.nih.gov/pubmed/29360748
http://dx.doi.org/10.3390/ijms19020288