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Molecular Understanding of the Activation of CB1 and Blockade of TRPV1 Receptors: Implications for Novel Treatment Strategies in Osteoarthritis

Osteoarthritis (OA) is a joint disease in which cartilage degenerates as a result of mechanical and biochemical changes. The main OA symptom is chronic pain involving both peripheral and central mechanisms of nociceptive processing. Our previous studies have implicated the benefits of dual- over sin...

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Detalles Bibliográficos
Autores principales: Mlost, Jakub, Kostrzewa, Magdalena, Malek, Natalia, Starowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855564/
https://www.ncbi.nlm.nih.gov/pubmed/29364174
http://dx.doi.org/10.3390/ijms19020342