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Disrupting the Btk Pathway Suppresses COPD-Like Lung Alterations in Atherosclerosis Prone ApoE(−/−) Mice Following Regular Exposure to Cigarette Smoke

Chronic obstructive pulmonary disease (COPD) is associated with severe chronic inflammation that promotes irreversible tissue destruction. Moreover, the most broadly accepted cause of COPD is exposure to cigarette smoke. There is no effective cure and significantly, the mechanism behind the developm...

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Detalles Bibliográficos
Autores principales: Florence, Jon M., Krupa, Agnieszka, Booshehri, Laela M., Gajewski, Adrian L., Kurdowska, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855565/
https://www.ncbi.nlm.nih.gov/pubmed/29364178
http://dx.doi.org/10.3390/ijms19020343