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Disrupting the Btk Pathway Suppresses COPD-Like Lung Alterations in Atherosclerosis Prone ApoE(−/−) Mice Following Regular Exposure to Cigarette Smoke
Chronic obstructive pulmonary disease (COPD) is associated with severe chronic inflammation that promotes irreversible tissue destruction. Moreover, the most broadly accepted cause of COPD is exposure to cigarette smoke. There is no effective cure and significantly, the mechanism behind the developm...
Autores principales: | Florence, Jon M., Krupa, Agnieszka, Booshehri, Laela M., Gajewski, Adrian L., Kurdowska, Anna K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855565/ https://www.ncbi.nlm.nih.gov/pubmed/29364178 http://dx.doi.org/10.3390/ijms19020343 |
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