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Mitochondrial BK Channel Openers CGS7181 and CGS7184 Exhibit Cytotoxic Properties

Potassium channel openers (KCOs) have been shown to play a role in cytoprotection through the activation of mitochondrial potassium channels. Recently, in several reports, a number of data has been described as off-target actions for KCOs. In the present study, we investigated the effects of BK(Ca)...

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Detalles Bibliográficos
Autores principales: Augustynek, Bartłomiej, Koprowski, Piotr, Rotko, Daria, Kunz, Wolfram S., Szewczyk, Adam, Kulawiak, Bogusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855575/
https://www.ncbi.nlm.nih.gov/pubmed/29370072
http://dx.doi.org/10.3390/ijms19020353