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Aging Donor-Derived Human Mesenchymal Stem Cells Exhibit Reduced Reactive Oxygen Species Loads and Increased Differentiation Potential Following Serial Expansion on a PEG-PCL Copolymer Substrate

Human mesenchymal stem cells (hMSCs) have been widely studied for therapeutic development in tissue engineering and regenerative medicine. They can be harvested from human donors via tissue biopsies, such as bone marrow aspiration, and cultured to reach clinically relevant cell numbers. However, an...

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Detalles Bibliográficos
Autores principales: Balikov, Daniel A., Crowder, Spencer W., Lee, Jung Bok, Lee, Yunki, Ko, Ung Hyun, Kang, Mi-Lan, Kim, Won Shik, Shin, Jennifer H., Sung, Hak-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855581/
https://www.ncbi.nlm.nih.gov/pubmed/29370101
http://dx.doi.org/10.3390/ijms19020359