Characterization and Oral Delivery of Proinsulin-Transferrin Fusion Protein Expressed Using ExpressTec

Proinsulin-transferrin fusion protein (ProINS-Tf) has been designed and successfully expressed from the mammalian HEK293 cells (HEK-ProINS-Tf). It was found that HEK-ProINS-Tf could be converted into an activated form in the liver. Furthermore, HEK-ProINS-Tf was demonstrated as an extra-long acting...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yu-Sheng, Zaro, Jennica L., Zhang, Deshui, Huang, Ning, Simon, Andrew, Shen, Wei-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855600/
https://www.ncbi.nlm.nih.gov/pubmed/29373562
http://dx.doi.org/10.3390/ijms19020378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855600/
https://www.ncbi.nlm.nih.gov/pubmed/29373562
http://dx.doi.org/10.3390/ijms19020378

Ejemplares similares