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How Do We Study the Dynamic Structure of Unstructured Proteins: A Case Study on Nopp140 as an Example of a Large, Intrinsically Disordered Protein

Intrinsically disordered proteins (IDPs) represent approximately 30% of the human genome and play key roles in cell proliferation and cellular signaling by modulating the function of target proteins via protein–protein interactions. In addition, IDPs are involved in various human disorders, such as...

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Detalles Bibliográficos
Autores principales: Na, Jung-Hyun, Lee, Won-Kyu, Yu, Yeon Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855603/
https://www.ncbi.nlm.nih.gov/pubmed/29382046
http://dx.doi.org/10.3390/ijms19020381