Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies

N-glycosylation profoundly affects the biological stability and function of therapeutic proteins, which explains the recent interest in glycoengineering technologies as methods to develop biobetter therapeutics. In current manufacturing processes, N-glycosylation is host-specific and remains difficu...

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Detalles Bibliográficos
Autores principales: Bennett, Lindsay D., Yang, Qiang, Berquist, Brian R., Giddens, John P., Ren, Zhongjie, Kommineni, Vally, Murray, Ryan P., White, Earl L., Holtz, Barry R., Wang, Lai-Xi, Marcel, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855643/
https://www.ncbi.nlm.nih.gov/pubmed/29385073
http://dx.doi.org/10.3390/ijms19020421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855643/
https://www.ncbi.nlm.nih.gov/pubmed/29385073
http://dx.doi.org/10.3390/ijms19020421

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