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Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies

N-glycosylation profoundly affects the biological stability and function of therapeutic proteins, which explains the recent interest in glycoengineering technologies as methods to develop biobetter therapeutics. In current manufacturing processes, N-glycosylation is host-specific and remains difficu...

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Detalles Bibliográficos
Autores principales:	Bennett, Lindsay D., Yang, Qiang, Berquist, Brian R., Giddens, John P., Ren, Zhongjie, Kommineni, Vally, Murray, Ryan P., White, Earl L., Holtz, Barry R., Wang, Lai-Xi, Marcel, Sylvain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855643/ https://www.ncbi.nlm.nih.gov/pubmed/29385073 http://dx.doi.org/10.3390/ijms19020421

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