Cargando…

The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes

Nephrotic syndrome is a kidney disease featured by heavy proteinuria. It is caused by injury to the specialized epithelial cells called “podocytes” within the filtration unit of the kidney, glomerulus. Previous studies showed that hyperactivation of the RhoGTPase, Rac1, in podocytes causes podocyte...

Descripción completa

Detalles Bibliográficos
Autores principales: Maier, Mirela, Baldwin, Cindy, Aoudjit, Lamine, Takano, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855701/
https://www.ncbi.nlm.nih.gov/pubmed/29415466
http://dx.doi.org/10.3390/ijms19020479