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The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes
Nephrotic syndrome is a kidney disease featured by heavy proteinuria. It is caused by injury to the specialized epithelial cells called “podocytes” within the filtration unit of the kidney, glomerulus. Previous studies showed that hyperactivation of the RhoGTPase, Rac1, in podocytes causes podocyte...
Autores principales: | Maier, Mirela, Baldwin, Cindy, Aoudjit, Lamine, Takano, Tomoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855701/ https://www.ncbi.nlm.nih.gov/pubmed/29415466 http://dx.doi.org/10.3390/ijms19020479 |
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