Telomere Length Dynamics and the Evolution of Cancer Genome Architecture

Telomeres are progressively eroded during repeated rounds of cell division due to the end replication problem but also undergo additional more substantial stochastic shortening events. In most cases, shortened telomeres induce a cell-cycle arrest or trigger apoptosis, although for those cells that b...

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Detalles Bibliográficos
Autores principales: Cleal, Kez, Norris, Kevin, Baird, Duncan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855704/
https://www.ncbi.nlm.nih.gov/pubmed/29415479
http://dx.doi.org/10.3390/ijms19020482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855704/
https://www.ncbi.nlm.nih.gov/pubmed/29415479
http://dx.doi.org/10.3390/ijms19020482

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