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Telomere Length Dynamics and the Evolution of Cancer Genome Architecture
Telomeres are progressively eroded during repeated rounds of cell division due to the end replication problem but also undergo additional more substantial stochastic shortening events. In most cases, shortened telomeres induce a cell-cycle arrest or trigger apoptosis, although for those cells that b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855704/ https://www.ncbi.nlm.nih.gov/pubmed/29415479 http://dx.doi.org/10.3390/ijms19020482 |